Cellular and Biochemical Engineering — U.S. National Science Foundation funding opportunity
U.S. National Science Foundation · Federal agency

Cellular and Biochemical Engineering

The Cellular and Biochemical Engineering program is part of the Engineering Biology and Health cluster, which includes also 1) Engineering of Biomedical Systems; 2) Biophotonics; 3) Nano-Biosensing; and 4) Disability and...

64
match
Deadline Fixed Location Alabama Type grant Level Federal Open posted Jun 6, 2025
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$8,200,000.
  • Issued by: U.S. National Science Foundation.
How was this generated?

The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

AI-generated. Always verify with the official source.

Deadline
Fixed
Total pool
$8.2M

About this opportunity

The Cellular and Biochemical Engineering program is part of the Engineering Biology and Health cluster, which includes also 1) Engineering of Biomedical Systems; 2) Biophotonics; 3) Nano-Biosensing; and 4) Disability and Rehabilitation Engineering. TheCellular and Biochemical Engineering (CBE)program supports fundamental engineering research that advances the understanding of cellular andbiomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced biomanufacturing in support of the therapeutic and biotechnology industries. A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the CBE program. Fundamental to many research projects in this area is the understanding of how biomolecules, cells and cell populations interact in the biomanufacturing environment, and how those molecular-level interactions lead to changes in behavior. The program encourages highly innovative and potentially transformative engineering research leading to novel bioprocessing and biomanufacturing approaches, and proposals that address emerging research areas and technologies that effectively integrate knowledge and practices from different disciplines while incorporating ongoing research into educational activities. Major areas of interest in the program include: Metabolic engineering and synthetic biology for biomanufacturing Quantitative systems biotechnology Cell culture technologies Protein and enzyme engineering Single cell dynamics and modeling in the context of biomanufacturing Development of novel "omics" tools for biomanufacturing applications All applications should include a description on the potential impact of proposed research on the associated biomanufacturing process. Proposals whose core innovation is tissue engineering or organ culture should be submitted to the Engineering ofBiomedicalSystems program (5345). The duration of unsolicited awards is generally one to three years. The typical award size for the program is around $100,000 per year with allowance for up to $200,000 per year for collaborative projects or those involving multiple investigators. Proposals requesting a substantially higher amount than this, without prior consultation with the Program Director, may be returned without review. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Please see the CAREER URLherefor more information. Proposals for Supplements: PIs are strongly encouraged to discuss their requests with the Program Director before submission of the proposal. Grants forRapid Response Research(RAPID)andEarly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Further details are available in theProposal and Award Policies and Procedures Guide(PAPPG)download foundhere.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that GOALI proposals must be submitted during the annual unsolicited proposal window for each program.

Funding agency

Tags

Want help applying?

Our specialists will check your eligibility, prepare the application, and walk you through every step — for free. Create a free account →

Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

How to apply

We don't have application instructions on file yet — head straight to the official source.

Apply on agency site
Tip from our team:

Read the agency's eligibility checklist before you start — it's almost always shorter than the full NOFO and will tell you in 90 seconds whether to keep going.

Need help getting in touch with the right agency contact?

Create a free account and our specialists will guide you through the application end-to-end.

Source documents

View on agency site
Canonical NOFO, application packet, and forms
No supplemental documents yet.

Direct downloads (NOFO PDFs, application forms, FAQs) will appear here once our team attaches them. For now, the agency site has the canonical packet.

Citation details

Source systemgrants.gov
Source ID359597
PostedJun 6, 2025

Frequently asked questions

No FAQs yet.

Have a question about this fund? Sign in to open a ticket about this fund.