DoD Gulf War Illness Innovative Treatment Evaluation Award — Defense Health Agency Contracting Activity - DHACA funding opportunity
Defense Health Agency Contracting Activity - DHACA · Federal agency

DoD Gulf War Illness Innovative Treatment Evaluation Award

The FY09 GWIRP is offering two award mechanisms to evaluate potential interventions for Gulf War Illness: the Innovative Treatment Evaluation Award (ITEA) and the Clinical Trial Award (CTA). The ITEA described in this Pr...

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Award $0 Deadline 6128 days ago Location Alabama Type grant Level Federal Closed posted Apr 21, 2009
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$2,880,000.
  • Next deadline: September 9, 2009.
  • Issued by: Defense Health Agency Contracting Activity - DHACA.
How was this generated?

The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

AI-generated. Always verify with the official source.

Award amount
$0
Deadline
6128 days ago
Sep 9, 2009
Total pool
$2.9M

About this opportunity

The FY09 GWIRP is offering two award mechanisms to evaluate potential interventions for Gulf War Illness: the Innovative Treatment Evaluation Award (ITEA) and the Clinical Trial Award (CTA). The ITEA described in this Program Announcement supports the initial evaluation of a treatment or intervention in smaller, early phase or pilot clinical trials (Phase II or I/II), and does not require preliminary data. [Note: All studies involving interventions, regardless of design, are considered clinical trials.] In contrast, the CTA supports proposals evaluating treatments of interventions in larger, more definitive clinical trials (Phase II or III), where preliminary and pre-clinical evidence indicates the potential for substantial benefit for veterans with GWI. Those interested in applying for the CTA mechanism should review the appropriate Program Announcement (http://cdmrp.army.mil/funding/gwirp.htm). The ITEA mechanism is being offered for the first time in FY09. The intent of the award is to provide support for the systematic evaluation of innovative treatment interventions not previously studied in Gulf War veterans, with the aim of improving their health and functional status. The results of preliminary studies funded by this award will support future development of larger efficacy studies of the proposed interventions. DOD GWIRP Innovative Treatment Evaluation Award 3 This award mechanism is intended to evaluate a broad scope of treatment approaches with potential for widespread, cost-effective application for GWI. Treatment approaches may include pharmacologic or other physiological interventions, including either conventional or complementary treatments, or combinations of these approaches. A variety of experimental and non-experimental study designs are acceptable under this award mechanism. The proposed study design will depend on the specific treatment or intervention to be assessed, resources available to clinical investigators, and the level of evidence currently available to support the proposed treatment for GWI. Examples of potential prospective designs may include systematic case series, prospective outcome evaluation studies, small-scale randomized trials, a combination of these, or other innovative prospective methods. Projects of interest include innovative treatment approaches currently in clinical use that have not been systematically evaluated for effectiveness in treating GWI but may have been evaluated in conditions with similarities to GWI. Also of interest are interventions based on biological alterations identified in veterans with GWI. Thus, the GWIRP will accept proposals not only for early pilot clinical trials supported by preliminary data but also for those based on sound scientific rationale without support from preliminary data. Important aspects of the Innovative Treatment Evaluation Award are: • The GWIRP views an innovative proposal as one that studies a previously untested treatment for GWI, including treatments that have been utilized for other chronic multi-symptom illnesses, though not yet studied in ill GW veterans. For example, a pharmacological treatment or nutritional supplement suggested by previous research to be beneficial for fibromyalgia or chronic fatigue syndrome could be evaluated in veterans with GWI under the ITEA. However, the focus must be clearly on Gulf War Illness and not on another disease process. • Preliminary data is allowed in this award but is not required, and the data does not necessarily need to come from Gulf War Illness research. If a proposal is submitted without preliminary data, the PI must provide a sound logical rationale to support potential effectiveness of the treatment in Gulf War Illness. Conversely, if there is significant preliminary and preclinical data reflecting considerable development of a treatment with applicability to GWI, the proposal would not be deemed innovative, in keeping with the intent of the ITEA.

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Geographic eligibility

  • Alabama
  • Alaska
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  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
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  • Kentucky
  • Louisiana
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  • Michigan
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  • Oregon
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  • Rhode Island
  • South Carolina
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  • Wisconsin
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  • District of Columbia

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Citation details

Source systemgrants.gov
Source ID46925
PostedApr 21, 2009

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