DOD Military Infectious Diseases Applied Research Award — Defense Health Agency Contracting Activity - DHACA funding opportunity
Defense Health Agency Contracting Activity - DHACA · Federal agency

DOD Military Infectious Diseases Applied Research Award

All applications MUST specifically address at least one of the MID-ARA Focus Areas related to combat-related or trauma-induced wound infections. Research projects incorporating high-throughput drug screening and/or in si...

96
match
Award $0 Deadline 4629 days ago Location Alabama Type grant Level Federal Closed posted Apr 24, 2013
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$11,100,000.
  • Next deadline: October 17, 2013.
  • Issued by: Defense Health Agency Contracting Activity - DHACA.
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The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

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Award amount
$0
Deadline
4629 days ago
Oct 17, 2013
Total pool
$11.1M

About this opportunity

All applications MUST specifically address at least one of the MID-ARA Focus Areas related to combat-related or trauma-induced wound infections. Research projects incorporating high-throughput drug screening and/or in silico modeling, as well as applications focused on areas other than those listed below should NOT be submitted. The MID-ARA Focus Areas are:• Development of new methods for rapid multi-pathogen/multi-phenotype detection of multidrug-resistant organisms (MDROs), nosocomial pathogens, and/or rapid multi-pathogen/multi-phenotype characterization of antimicrobial resistance patterns.• Development of assays for host immune response biomarkers for diagnosis or prognosis (with associated outcomes) of infection to inform clinical wound management decisions ( optimal wound closure time, optimal duration of antibiotics for osteomyelitis).• Development and preclinical testing of novel chemotypes (chemical classes/materials), biologics as potential therapeutics or prophylactics for wound infection, and/or biofilm propagation. Innovative treatment approaches ( peptides, quorum-sensing inhibitors, and host immunoaugmentation, etc.) are encouraged.NOTES FOR ALL FOCUS AREAS:• Preference will be given to approaches that address infections with one or more multi-drug resistant organisms (MDROs), particularly, Acinetobacter baumannii, Pseudomonas aeruginosa, extended-spectrum beta-lactamase producing Enterobacteriaceae (including Escherichia coli and Klebsiella pneumoniae), and methicillin-resistant Staphylococcus aureus (MRSA), and/or invasive fungal (mold) pathogens.• Preference will be given to studies leading toward topical treatments for prevention and management of wound infection. Overview: The FY14 DMRDP MID-ARA seeks applied research applications focused on the reduction of combat-related or trauma-induced wound infection morbidity and mortality. These awards are expected to yield potential health technologies positioned for human testing. The intent of the FY14 DMRDP MID-ARA is to support:• Hypothesis-testing and/or proof-of-concept studies in in vitro and/or in vivo models;• Refinement of concepts and ideas into potential solutions with a view toward evaluating technical feasibility of emerging promising new products;• Evaluation, maturation, and/or down-selection of potential product candidates (drugs, biologic/vaccine constructs, or devices/systems) in vitro and/or in vivo and;• Completion of preclinical safety and/or toxicity studies sufficient to support Investigational New Drug/Investigational Device Exemption (IND/IDE) applications.Awards may support studies with human subjects but may not be used to support clinical trials. A clinical trial is defined as a prospective accrual of human subjects where an intervention ( procedure, rehabilitative modality, behavioral intervention, or other) is tested on a human subject for a measurable outcome with respect to exploratory , and/or efficacy. This outcome represents a direct effect on the human subject of that intervention or interaction.Awards may not be used to support fundamental basic research. Basic research is defined as research directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications toward process or products in mind.Presentation of preliminary data is required. Investigators must demonstrate logical reasoning and a sound scientific rationale established through a critical review and analysis of the literature for the application to be competitive. Research projects should include a well-formulated, testable hypothesis based on strong scientific rationale.Partnering Principal Investigator (PI) Option: The FY14 DMRDP MID-ARA mechanism supports applications that include meaningful and productive collaborations.

Funding agency

Defense Health Agency Contracting Activity - DHACA
Federal agency

Tags

Healthcare & Biotech Education & Research Veterans Transportation & Logistics Science, Tech & Engineering (STEM)
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Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

How to apply

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Source documents

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Canonical NOFO, application packet, and forms
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Citation details

Source systemgrants.gov
Source ID231513
PostedApr 24, 2013

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