Defense Health Agency Contracting Activity - DHACA
· Federal agency
DoD Peer Reviewed Orthopaedic, Applied Research Award
Orthopaedic injuries have a profound impact on military readiness and return to work/activity/duty. In the military, extremity battle wounds comprise approximately 50% of injuries reported in the Joint Theatre Trauma Reg...
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Deadline1377 days agoLocationAlabamaTypegrantLevelFederalClosedposted Apr 8, 2022
✦ AI Summary
Who can apply: Federal-level applicants (see eligibility for details).
Funding amount: total funding pool ~$3,620,000.
Next deadline: September 13, 2022.
Issued by: Defense Health Agency Contracting Activity - DHACA.
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Deadline
1377 days ago
Sep 13, 2022
Total pool
$3.6M
About this opportunity
Orthopaedic injuries have a profound impact on military readiness and return to work/activity/duty. In the military, extremity battle wounds comprise approximately 50% of injuries reported in the Joint Theatre Trauma Registry. Additionally, orthopaedic injuries and conditions that occur outside of combat ( during training, leisure activities, resultant from old injuries, etc.) present one of the greatest threats to the readiness of our Service Members and military. Early rehabilitation of orthopaedic injuries in both civilian and military populations have led to better outcomes, particularly in the prevention of secondary complications and in minimizing morbidity. Availability of orthopaedic care and treatment as early as possible, or as close to the point of injury as possible, also minimizes limb loss and affects military readiness. The PRORP is interested in supporting research that will have an impact on the lives of all individuals that have sustained a major musculoskeletal injury.The FY22 PRORP ARA seeks applied research applications focused on advancing optimal treatment and restoration of function for individuals with musculoskeletal injuries sustained during combat, combat-related activities, and non-battle injuries that impact unit readiness and the ability to return to duty/work. Applicants are encouraged to address how the proposed research will support patient care and allow patients to more quickly return to duty/work. It is expected that any research findings would also provide benefit to the general population. To meet the intent of the award mechanism, applications must specifically address an FY22 PRORP ARA Focus Area, listed in Section II.A.1, above.The FY22 PRORP ARA is focused on applied research, defined as work that refines concepts and ideas into potential solutions with a view toward evaluating technical feasibility of promising new knowledge products, pharmacologic agents, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance, and/or emerging approaches and technologies.Research Scope: Research proposed under the FY22 PRORP ARA may include small- to large-scale projects. Upon successful completion, the proposed research is expected to yield knowledge technologies that have the potential to advance toward clinical translation. Strong transition plans are expected.Inclusion of preliminary and/or published data relevant to the proposed research is required. Applicants must demonstrate logical reasoning for the proposed work. To be competitive, the application must include a sound scientific rationale and a well-formulated, testable hypothesis established through a critical review and analysis of the literature.Studies allowed under the FY22 PRORP ARA may include, but are not limited to:• Refinement of concepts and ideas into potential solutions, or research tools, with a view toward evaluating technical feasibility of emerging promising new knowledge products.• Evaluation, maturation, and/or down-selection of potential product candidates (drugs, biologic constructs, or devices/systems) in vitro and/or in vivo.• Preparation activities needed to support a future clinical trial or regulatory submission.Awards may not be used to support fundamental basic research. Basic research is defined as research directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications toward process or products in mind.Applications to the FY22 PRORP ARA mechanism must support preclinical applied research and may not be used for clinical research studies. Clinical research is defined as: (1) Patient-oriented research. Research conducted with human subjects (or on material of human origin such as cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects.
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