DoD Prostate Cancer, Prostate Cancer Pathology Resource Network Award — Defense Health Agency Contracting Activity - DHACA funding opportunity
Defense Health Agency Contracting Activity - DHACA · Federal agency

DoD Prostate Cancer, Prostate Cancer Pathology Resource Network Award

The FY20 PCRP Prostate Cancer Pathology Resource Network (PCPRN) Award is intended to provide infrastructure support for the development and maintenance of a prostate cancer biorepository through a collaborative network...

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Deadline 2095 days ago Location Alabama Type grant Level Federal Closed posted May 8, 2020
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$9,600,000.
  • Next deadline: September 24, 2020.
  • Issued by: Defense Health Agency Contracting Activity - DHACA.
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Deadline
2095 days ago
Sep 24, 2020
Total pool
$9.6M

About this opportunity

The FY20 PCRP Prostate Cancer Pathology Resource Network (PCPRN) Award is intended to provide infrastructure support for the development and maintenance of a prostate cancer biorepository through a collaborative network across multiple institutions that will facilitate the distribution of high-quality human prostate cancer biospecimens. A major focus of the Network must be placed on the acquisition and distribution of specimens in limited supply, such as:• Castration-resistant disease, metastatic disease, primary untreated “de novo” metastatic disease as defined by STAMPEDE or high-risk disease defined by CHAARTED, tumors of the aggressive variant phenotype• Disproportionately affected (African , etc.) and underserved (uninsured, rural communities, etc.) populations• Active surveillance populations• Longitudinal/sequential specimensThe Network must also manage data derived from the distributed biospecimens, including digital images of the hematoxylin and eosin (H&E)-stained samples and blood-based germline assessments.Applications should describe how the development of the Network biorepository will enable the prostate cancer research community to address the FY20 PCRP Overarching Challenges by utilizing Network biospecimens. Applications should propose a clearly defined mission that will guide the proposed Network’s biospecimen data collectioncesses.The Network will consist of three to five Pathology Resource Sites, one of which will also serve as the Coordinating Center. These organizations will be jointly responsible for developing and maintaining the biorepository for prostate cancer research. The Coordinating Center and Pathology Resource Sites should together design the proposed biorepository. It is expected that the Coordinating Center will provide unique resources that may not be available at the Pathology Resource Sites and can be leveraged for the biorepository as a whole. Additionally, Pathology Resource Sites should each possess the ability to derivatize proteins from biospecimens and utilize both standard and state-of-the-art technologies ( laser capture microdissection, tissue microarrays) to provide the necessary biospecimen processing for a large range of prostate cancer research studies. Both and international organizations should be considered for inclusion in applications for this award. The Pathology Resource Sites should be selected for the individual contributions each can make to the biorepository; the contributions need not be equal but rather of unique value to the biorepository as a whole. If the contributions vary significantly among Pathology Resource Sites, variance in the budgets allocated to sites should be well described in the budget justification.The PCPRN Coordinating Center, in addition to functioning as a Pathology Resource Site, will serve as the nexus for Network information and planning, providing data management support to Pathology Resource Sites in implementing Network policies and standard operating procedures (SOPs). Therefore, the Coordinating Center will have multidisciplinary expertise and extensive experience in multi-institutional collaborations in prostate cancer research. Applications from organizations with resources (such as sufficient equipment for biorepository functions, pathology and histochemistry infrastructure, and informatics and information infrastructure to support connectivity between the Coordinating Center and Pathology Resource Sites for data transfer) already in place to support the development of a biorepository are encouraged. Principal Investigators (PIs) are expected to have experience and expertise in human biospecimen distribution, and in developing and operating a biospecimen repository.

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Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

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Citation details

Source systemgrants.gov
Source ID326928
PostedMay 8, 2020

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