Engineering of Biomedical Systems — U.S. National Science Foundation funding opportunity
U.S. National Science Foundation · Federal agency

Engineering of Biomedical Systems

TheEngineering of Biomedical Systems program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering...

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Deadline Fixed Location Alabama Type grant Level Federal Open posted Jun 6, 2025
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$10,400,000.
  • Issued by: U.S. National Science Foundation.
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The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

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Deadline
Fixed
Total pool
$10.4M

About this opportunity

TheEngineering of Biomedical Systems program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Disability and Rehabilitation Engineering program. The goal of theEngineering of Biomedical Systems (EBMS) program is to provide opportunities for creating fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term. Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences. Projects may include: enabling tools applied to understand or control living systems; fundamental improvements in deriving information from organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering: Developmentof validated models (living or computational) of healthy and pathological tissues and organ systems that can support improved fundamental understanding of these systems or development and testing of medical interventions; Designand validation of systems that integrate living and non-living componentsfor improved treatment ofdisease or injury; Advancedbiomanufacturing of three-dimensional tissues and organs; Design and subsequent application of technologies andtools, including those that leverage an organism’s microbiome, toinvestigate fundamental physiological and pathophysiological processes;and Application of engineering tools and principles, including mathematical modeling, to quantitatively study the immune system in health and disease and to develop techniques for controlling and modulating a host’s immune response to challenges such as infectious disorders, wounds, etc. Innovative proposals outside of these specific areas of biomedical engineering may be considered.However, prior to submission, it is strongly recommended that the PIs contact the program director to avoid the possibility of the proposal being returned without review. Related programs also fund biomedical engineering research, and PIs are encouraged to examine these to find the appropriate program for submission. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function in normal and pathological conditions, effective disease diagnosis and/or treatment, or improved health care delivery. The EBMS program does not support proposals having as their central theme drug design and delivery, the development of biomedical devices that do not include a living biological component, or thedevelopment of animal models of disease.For consideration by the EBMS program, proposals that advance the design of tools or technologies should also apply those technologies to advance knowledge in biomedical science.NSF does not support clinical trials; however, feasibility studies involving human volunteers may be supported if appropriate to the project objectives. Furthermore, although research on biomaterials, cellular biomechanics, or manufacturing systems may constitute a part of the proposed studies, such research cannot be the central theme or key focus area of the proposed work.Biomaterials-focused projects should consider the Biomaterials (BMAT) program in the Division of Materials Research (DMR), while cellular biomechanics projects should consider the Biomechanics and Mechanobiology (BMMB) program and manufacturing systems proposals should consider the Advanced Manufacturing(AM) program, both in the Division of Manufacturing Innovation (CMMI).

Funding agency

U.S. National Science Foundation
Federal agency

Tags

Healthcare & Biotech Manufacturing Education & Research Transportation & Logistics Science, Tech & Engineering (STEM)
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Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

How to apply

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Source documents

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Canonical NOFO, application packet, and forms
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Citation details

Source systemgrants.gov
Source ID359508
PostedJun 6, 2025

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