Nano-Biosensing — U.S. National Science Foundation funding opportunity
U.S. National Science Foundation · Federal agency

Nano-Biosensing

The Nano-Biosensing program is part of the Engineering Biology and Health cluster, which includes also 1) Cellular and Biochemical Engineering; 2) Engineering of Biomedical Systems; 3) Biophotonics; and 4) Disability and...

67
match
Deadline Fixed Location Alabama Type grant Level Federal Open posted Jun 6, 2025
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: total funding pool ~$7,600,000.
  • Issued by: U.S. National Science Foundation.
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The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

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Deadline
Fixed
Total pool
$7.6M

About this opportunity

The Nano-Biosensing program is part of the Engineering Biology and Health cluster, which includes also 1) Cellular and Biochemical Engineering; 2) Engineering of Biomedical Systems; 3) Biophotonics; and 4) Disability and Rehabilitation Engineering. The Nano-Biosensing program supports fundamental engineering research on devices and methods for measurement and quantification of biological analytes. Proposals that incorporate emerging nanotechnology methods are especially encouraged. Areas of interest include: Multi-purpose sensor platforms that exceed the performance of current state-of-the-art devices. Novel transduction principles, mechanisms and sensor designs suitable for measurement in practical matrix and sample-preparation-free approaches. These include error-free detection of pathogens and toxins in food matrices, waterborne in body fluids, and others that improve human condition. Nano-biosensors that enable measurement of biomolecular interactions in their native states, transmembrane transport, intracellular transport and reactions, and other biological phenomena. Studies that examine intracellular measurements must include discussion on the significance of the measurement. Proposals should clearly identify the proposed problem to be solved, describe why the proposed approach is superior to current available methods, and articulate the benefit of solving the identified problem for the society at large. Sensor designs that yield reliable measurements are encouraged. While sensitivity is important, it cannot be at the expense of reproducibility. Every application must include research strategies for addressing reproducibility of measurement and sensor response, as well as approaches that reduce errors. The program does not support applications with incremental improvements of existing approaches and technologies. Projects that do not include experimental characterization of sensor responses to biological analytes are discouraged, and may be returned without a review. Studies on surface functionalization and immobilization of bio-recognition molecules, and/or orientation of them are not encouraged. Research that is focused on new recognition chemistry is also discouraged. The novelty or potentially transformative nature of the research must be included in the Project Summary. The last line in Project Summary must include three key phrasesthat describe: (1) sensor transduction principles, (2) type of biological analytes, (3) potential application areas. Innovative ideas outside of the above specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the Program Director to avoid the proposal being returned without review. NOTE: Projects related to water quality may be jointly supported with the Environmental Engineering program (CBET 1440). Photonic nanosensors with medical applications and/or imaging should be submitted to Biophotonics (CBET 7236). The Nano-Biosensing program does not support imaging applications. The duration of unsolicited awards is generally one to three years. The typical award size for the program is approximately $100,000 per year. Proposals requesting a substantially higher amount than this, without prior consultation with the Program Director, may be returned without review. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years.

Funding agency

U.S. National Science Foundation
Federal agency

Tags

Healthcare & Biotech Technology & Software Education & Research Climate & Environment Transportation & Logistics Science, Tech & Engineering (STEM)
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Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

How to apply

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Source documents

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Canonical NOFO, application packet, and forms
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Citation details

Source systemgrants.gov
Source ID359608
PostedJun 6, 2025

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