Diet, Epigenetic Events, and Cancer Prevention (R21) — National Institutes of Health funding opportunity
National Institutes of Health · Federal agency

Diet, Epigenetic Events, and Cancer Prevention (R21)

The aim of this funding opportunity announcement (FOA) is to promote clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttransla...

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Award Up to $200k Deadline Fixed Location Alabama Type grant Level Federal Open posted May 16, 2006
✦ AI Summary
  • Who can apply: Federal-level applicants (see eligibility for details).
  • Funding amount: up to $200,000.
  • Issued by: National Institutes of Health.
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The “key facts” mode pulls structured fields directly from the official source posting (amount, deadline, eligibility tags). The AI mode adds a short plain-English narrative on top, generated from the same source. Always verify with the agency before applying.

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Award amount
Up to $200k
Deadline
Fixed

About this opportunity

The aim of this funding opportunity announcement (FOA) is to promote clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttranslational modification, and other epigenetic processes involved in cancer prevention and development. Another important aim of this initiative is to encourage collaborations between nutrition and epigenetic experts to study bioactive food components with cancer-preventative properties and to examine key epigenetic events in cancer processes ( carcinogen metabolism, cell apoptosis) in order to begin to establish linkages between epigenetics, methylation patterns, and tumor incidences/behaviors. NIAAA is specifically interested in receiving applications that examine the impact(s) of chronic alcohol consumption on levels of folate, and possible associations with DNA methylation and cancer. NIDDK is particularly interested in receiving applications that address normal and neoplastic conditions focusing on the impact of epigenetics on cell division, differentiation, and/or apoptosis in the gastrointestinal (GI) tract and related organs. -This FOA utilizes the NIH exploratory/developmental (R21) grant mechanism and runs in parallel with two other FOAs of identical scientific scope, one being PA-06-414, which solicits applications using the NIH Small Grant (R03) award mechanism, and the other being PA-06-412 which solicits applications using the NIH Research Project Grant (R01) award mechanism. -Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications; therefore, the anticipated number of awards is not known. -Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism costs of the applications received. -The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over an R21 2-year period, with no more than $200,000 in direct costs allowed in any single year (note that consortium [third party] facilities and administrative costs are not included in the direct cost limitation). -Eligible organizations include: for-profit organizations; non-profit organizations; public or private institutions, such as and laboratories; units of State and local governments; eligible agencies of the Federal government; domestic or foreign institutions/organizations; faith-based or community-based organizations; Indian/Native American Tribal Indian/Native American Tribal and Indian/Native American Tribally Designated Organizations. -Eligible Project Directors/Principal Investigators (PDs/PIs) include any individual from the institution with the resources necessary to carry out the proposed research. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. -Applicants may submit more than one application, provided each application is scientifically distinct.

Funding agency

National Institutes of Health
Federal agency

Tags

Healthcare & Biotech Nonprofit & Community Small Business Education & Research Construction & Housing Tribal & Native Minority-Owned Business
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Who can apply

Eligibility details aren't on file yet — check the agency source link in the Documents tab for the latest rules.

Geographic eligibility

  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • North Dakota
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
  • Wyoming
  • District of Columbia

How to apply

We don't have application instructions on file yet — head straight to the official source.

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Source documents

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Canonical NOFO, application packet, and forms
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Direct downloads (NOFO PDFs, application forms, FAQs) will appear here once our team attaches them. For now, the agency site has the canonical packet.

Citation details

Source systemgrants.gov
Source ID43703
PostedMay 16, 2006

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